Anti-CD3E Mouse Monoclonal Antibody (CF405S) [clone: B-B12]

Supplier: Biotium

BNC041052-100 BNC041052-500

75895-362EA 325.12 CAD

75895-362 75895-364

Anti-CD3E Mouse Monoclonal Antibody (CF405S) [clone: B-B12]

Antibodies

This antibody recognizes five invariable CD3 chains (designated as and ) with molecular weight ranging from 16-28 kDa. CD3 is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. The CD3 complex is closely associated at the lymphocyte cell surface with T cell antigen receptor (TCR) and is involved in transducing antigen-recognition signals into cytoplasm of T cells and in regulating the cell surface expression of the TCR complex.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: CD3E
Clonality: Monoclonal
Clone: B-B12
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1, kappa2a, kappa
Reactivity: Human

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