Anti-CEACAM1 & CEACAM5 Mouse Monoclonal Antibody (CF594) [clone: C66/1030]

Supplier: Biotium

BNC941030-100 BNC941030-500

75916-792EA 325.12 CAD

75916-792 75918-716

Anti-CEACAM1 & CEACAM5 Mouse Monoclonal Antibody (CF594) [clone: C66/1030]

Antibodies

This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA positive) from pleural mesotheliomas (rarely or weakly CEA positive) . Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: CEACAM1 & CEACAM5
Clonality: Monoclonal
Clone: C66/1030
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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