Anti-THY1 Mouse Monoclonal Antibody (Biotin) [clone: AF-9]

Supplier: Biotium

BNCB0987-100 BNCB0987-500

75908-434EA 325.12 CAD

75908-434 75908-436

Anti-THY1 Mouse Monoclonal Antibody (Biotin) [clone: AF-9]

Antibodies

This antibody recognizes a protein of 18-35 kDa, identified as CD90 (also known as Thy1). CD90 is a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35 kDa) inserted into the cell membrane via a GPI anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblast and stromal cell lines, expressed on all thymocytes and peripheral T cells in mice, but in humans expressed only on small % fetal thymocytes, 10-40% of CD34 cells in bone marrow, and <1% of CD3 CD4 lymphocytes in peripheral circulation. It is also expressed by human lymph node HEV endothelium but not other endothelia. Lastly, it is expressed by a limited number of lymphoblastoid and leukemic cell lines.

Type: Primary
Antigen: THY1
Clonality: Monoclonal
Clone: Clone AF-9
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Cow, Human

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