Anti-BAX Mouse Monoclonal Antibody (CF488A) [clone: BAX/962]

Supplier: Biotium

BNC880962-100 BNC880962-500
75884-422EA 325.12 CAD
75884-422 75884-424
Anti-BAX Mouse Monoclonal Antibody (CF488A) [clone: BAX/962]
Antibodies
This antibody recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: BAX
Clonality: Monoclonal
Clone: Clone BAX/962
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Monkey
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