Anti-UACA Mouse Monoclonal Antibody (CF647) [clone: AE-5]

Supplier: Biotium

BNC470956-100 BNC470956-500

75978-804EA 325.12 CAD

75978-804 75978-806

Anti-UACA Mouse Monoclonal Antibody (CF647) [clone: AE-5]

Antibodies

UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: UACA
Clonality: Monoclonal
Clone: Clone AE-5
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Mouse

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