Anti-MUC5AC Mouse Monoclonal Antibody [clone: MUC5AC/917]

Supplier: Biotium

BNUB0917-100 BNUB0917-500

75963-256EA 380.65 CAD

75963-256 75963-258

Anti-MUC5AC Mouse Monoclonal Antibody [clone: MUC5AC/917]

Antibodies

Mucin 5AC glycoprotein (MUC5AC) is a 641 kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming secreted mucin that is found in normal gastric and tracheo-bronchial mucosa, but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

Type: Primary
Antigen: MUC5AC
Clonality: Monoclonal
Clone: Clone MUC5AC/917
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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