Anti-MITF Mouse Monoclonal Antibody (CF647) [clone: MITF/915]

Supplier: Biotium

BNC470915-100 BNC470915-500
75961-622EA 325.12 CAD
75961-622 75961-624
Anti-MITF Mouse Monoclonal Antibody (CF647) [clone: MITF/915]
Antibodies
MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that regulates the development and survival of melanocytes and retinal pigment epithelium, and also is involved in transcription of pigmentation enzyme genes such as tyrosinase TRP1 and TRP2. MITF has been shown to be phosphorylated by MAP kinase in response to c-kit activation, resulting in upregulation of MITF transcriptional activity. Mutations of the MITF gene are associated with the autosomal dominant hereditary deafness and pigmentation condition, Waardenburg SyndromeMore Product Information
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