Anti-CD34 Mouse Monoclonal Antibody (CF594) [clone: QBEnd/10 HPCA1/763]

Supplier: Biotium

BNC940904-100 BNC940904-500

75894-678EA 325.12 CAD

75894-678 75894-680

Anti-CD34 Mouse Monoclonal Antibody (CF594) [clone: QBEnd/10 HPCA1/763]

Antibodies

This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi's sarcoma, but with a lower specificity.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: CD34
Clonality: Monoclonal
Clone: QBEnd/10 HPCA1/763
Conjugation: CF594
Epitope:
Host: Mouse
Reactivity: Human
Isotype: IgGs

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