Anti-AMPD3 Mouse Monoclonal Antibody [clone: AMPD3/901]

Supplier: Biotium

BNUB0901-100 BNUB0901-500

75881-640EA 380.65 CAD

75881-640 75881-642

Anti-AMPD3 Mouse Monoclonal Antibody [clone: AMPD3/901]

Antibodies

This antibody recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.

Type: Primary
Antigen: AMPD3
Clonality: Monoclonal
Clone: AMPD3/901
Conjugation: Unconjugated
Epitope:
Host: Mouse
Reactivity: Human
Isotype: IgG2b, kappa

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