Anti-AR Mouse Monoclonal Antibody (Biotin) [clone: AR441]

Supplier: Biotium

BNCB0881-100 BNCB0881-500
75881-806EA 325.12 CAD
75881-806 75881-808
Anti-AR Mouse Monoclonal Antibody (Biotin) [clone: AR441]
Antibodies
This antibody recognizes a protein of 110 kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.

Type: Primary
Antigen: AR
Clonality: Monoclonal
Clone: AR441
Conjugation: Biotin
Epitope:
Host: Mouse
Reactivity: Human
Isotype: IgG1, kappa
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