Anti-AR Mouse Monoclonal Antibody (CF555) [clone: AR441]

Supplier: Biotium

BNC550881-100 BNC550881-500

75881-826EA 325.12 CAD

75881-826 75881-828

Anti-AR Mouse Monoclonal Antibody (CF555) [clone: AR441]

Antibodies

This antibody recognizes a protein of 110 kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®555 is a bright orange-red fluorescent dye (Ex/Em 555/565 nm) that is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: AR
Clonality: Monoclonal
Clone: AR441
Conjugation: CF555
Epitope:
Host: Mouse
Reactivity: Human
Isotype: IgG1, kappa

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