Anti-CD99 Mouse Monoclonal Antibody (CF660R) [clone: MIC2/877]

Supplier: Biotium

BNC610877-100 BNC610877-500

75910-862EA 325.12 CAD

75910-862 75910-864

Anti-CD99 Mouse Monoclonal Antibody (CF660R) [clone: MIC2/877]

Antibodies

This antibody recognizes a sialoglycoprotein of 27-32 kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32 kDa (p30/32).Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis.CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing s sarcoma cells and primitive peripheral neuroectodermal tumors.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®660R is a far-red fluorescent dye (Ex/Em 663/682 nm) with superior brightness and unrivaled photostability among spectrally similar dyes.

Type: Primary
Antigen: CD99
Clonality: Monoclonal
Clone: Clone MIC2/877
Conjugation: CF660R
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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