Anti-HSPB1 Mouse Monoclonal Antibody (CF594) [clone: G3.1]

Supplier: Biotium

BNC940861-100 BNC940861-500

75951-594EA 325.12 CAD

75951-594 75951-596

Anti-HSPB1 Mouse Monoclonal Antibody (CF594) [clone: G3.1]

Antibodies

This MAb reacts specifically with heat shock protein HSP27 in human and monkey tissues and cell lines such as MCF-7. HSP27, also referred to as the Estrogen-Regulated24Kprotein and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian α-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore HSP27 may be useful in classifying various hormone sensitive tumors.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: HSPB1
Clonality: Monoclonal
Clone: Clone G3.1
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Chicken, Chimpanzee, Human, Monkey, Mouse, Rat, Sheep

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