Anti-TYRP1 Mouse Monoclonal Antibody (CF488A) [clone: TA99]

Supplier: Biotium

BNC880806-100 BNC880806-500

75977-852EA 325.12 CAD

75977-852 75977-854

Anti-TYRP1 Mouse Monoclonal Antibody (CF488A) [clone: TA99]

Antibodies

This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: TYRP1
Clonality: Monoclonal
Clone: Clone TA99
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human, Mouse

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