Anti-TYRP1 Mouse Monoclonal Antibody (CF405S) [clone: TA99]

Supplier: Biotium

BNC040806-100 BNC040806-500

75977-848EA 325.12 CAD

75977-848 75977-850

Anti-TYRP1 Mouse Monoclonal Antibody (CF405S) [clone: TA99]

Antibodies

This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: TYRP1
Clonality: Monoclonal
Clone: Clone TA99
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human, Mouse

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