Anti-INS Mouse Monoclonal Antibody (CF488A) [clone: IRDN/805]

Supplier: Biotium

BNC880805-100 BNC880805-500

75955-016EA 325.12 CAD

75955-016 75955-018

Anti-INS Mouse Monoclonal Antibody (CF488A) [clone: IRDN/805]

Antibodies

This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: INS
Clonality: Monoclonal
Clone: Clone IRDN/805
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Cow, Human, Mouse, Pig, Rabbit

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