Anti-SILV Mouse Monoclonal Antibody (CF647) [clone: PMEL/783]

Supplier: Biotium

BNC470783-100 BNC470783-500

75971-032EA 325.12 CAD

75971-032 75971-034

Anti-SILV Mouse Monoclonal Antibody (CF647) [clone: PMEL/783]

Antibodies

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: SILV
Clonality: Monoclonal
Clone: Clone PMEL/783
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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