Anti-CDKN1B Mouse Monoclonal Antibody (CF405S) [clone: DCS-72.F6]

Supplier: Biotium

BNC040771-100 BNC040771-500

75967-252EA 325.12 CAD

75967-252 75967-254

Anti-CDKN1B Mouse Monoclonal Antibody (CF405S) [clone: DCS-72.F6]

Antibodies

This antibody recognizes a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: CDKN1B
Clonality: Monoclonal
Clone: DCS-72.F6
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Monkey, Mouse, Rat

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