Anti-CHGA Mouse Monoclonal Antibody (Biotin) [clone: CHGA/765]

Supplier: Biotium

BNCB0765-100 BNCB0765-500

75909-842EA 325.12 CAD

75909-842 75909-844

Anti-CHGA Mouse Monoclonal Antibody (Biotin) [clone: CHGA/765]

Antibodies

Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Type: Primary
Antigen: CHGA
Clonality: Monoclonal
Clone: CHGA/765
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human

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