Anti-NEFH & NEFL Mouse Monoclonal Antibody (CF568) [clone: NF421 NFL/736]

Supplier: Biotium

BNC680756-100 BNC680756-500

75965-746EA 325.12 CAD

75965-746 75965-748

Anti-NEFH & NEFL Mouse Monoclonal Antibody (CF568) [clone: NF421 NFL/736]

Antibodies

This MAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Type: Primary
Antigen: NEFH & NEFL
Clonality: Monoclonal
Clone: Clone NF421 NFL/736
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Chicken, Human, Mouse, Pig, Rat

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