Anti-TAG-72 Mouse Monoclonal Antibody (Biotin) [clone: B72.3 CC49]

Supplier: Biotium

BNCB0738-100 BNCB0738-500

75974-384EA 325.12 CAD

75974-384 75974-386

Anti-TAG-72 Mouse Monoclonal Antibody (Biotin) [clone: B72.3 CC49]

Antibodies

This antibody recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Type: Primary
Antigen: TAG-72
Clonality: Monoclonal
Clone: Clone B72.3 CC49
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Cow, Dog, Human, Rat

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