Anti-TAG-72 Mouse Monoclonal Antibody (CF594) [clone: B72.3 CC49]

Supplier: Biotium

BNC940738-100 BNC940738-500
75975-892EA 325.12 CAD
75975-892 75975-894
Anti-TAG-72 Mouse Monoclonal Antibody (CF594) [clone: B72.3 CC49]
Antibodies
This antibody recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: TAG-72
Clonality: Monoclonal
Clone: Clone B72.3 CC49
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Cow, Dog, Human, Rat
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