Anti-NEFL Mouse Monoclonal Antibody (Biotin) [clone: NFL/736]

Supplier: Biotium

BNCB0736-100 BNCB0736-500

75965-864EA 325.12 CAD

75965-864 75965-866

Anti-NEFL Mouse Monoclonal Antibody (Biotin) [clone: NFL/736]

Antibodies

This MAb reacts with a 68 kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Type: Primary
Antigen: NEFL
Clonality: Monoclonal
Clone: Clone NFL/736
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Chicken, Cow, Human, Pig, Rat

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