Anti-XRCC6 (p70) & XRCC5 (p80) Mouse Monoclonal Antibody (CF405S) [clone: KU729]

Supplier: Biotium

BNC040729-100 BNC040729-500

75956-160EA 325.12 CAD

75956-160 75956-162

Anti-XRCC6 (p70) & XRCC5 (p80) Mouse Monoclonal Antibody (CF405S) [clone: KU729]

Antibodies

This antibody recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. This MAb This antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: XRCC6 (p70) & XRCC5 (p80)
Clonality: Monoclonal
Clone: Clone KU729
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Primates

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