Anti-MLANA Mouse Monoclonal Antibody (CF405S) [clone: M2-7C10 M2-9E3]

Supplier: Biotium

BNC040705-100 BNC040705-500

75960-440EA 325.12 CAD

75960-440 75960-442

Anti-MLANA Mouse Monoclonal Antibody (CF405S) [clone: M2-7C10 M2-9E3]

Antibodies

This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: MLANA
Clonality: Monoclonal
Clone: Clone M2-7C10 M2-9E3
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human, Mouse, Rat

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