Anti-MLANA Mouse Monoclonal Antibody (CF488A) [clone: HMB45 M2-7C10 M2-9E3 T311]

Supplier: Biotium

BNC880701-100 BNC880701-500

75960-064EA 325.12 CAD

75960-064 75960-066

Anti-MLANA Mouse Monoclonal Antibody (CF488A) [clone: HMB45 M2-7C10 M2-9E3 T311]

Antibodies

This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: MLANA
Clonality: Monoclonal
Clone: Clone HMB45 M2-7C10 M2-9E3 T311
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human

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