Anti-NCAM1 Mouse Monoclonal Antibody (Biotin) [clone: 123A8 (same as 56C04)]

Supplier: Biotium

BNCB0692-100 BNCB0692-500

75912-292EA 325.12 CAD

75912-292 75912-294

Anti-NCAM1 Mouse Monoclonal Antibody (Biotin) [clone: 123A8 (same as 56C04)]

Antibodies

This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Type: Primary
Antigen: NCAM1
Clonality: Monoclonal
Clone: Clone 123A8 (same as 56C04)
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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