Anti-KRT8 & KRT18 Mouse Monoclonal Antibody (Biotin) [clone: K8.8 DC10]

Supplier: Biotium

BNCB0691-100 BNCB0691-500

75923-290EA 325.12 CAD

75923-290 75923-292

Anti-KRT8 & KRT18 Mouse Monoclonal Antibody (Biotin) [clone: K8.8 DC10]

Antibodies

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.

Type: Primary
Antigen: KRT8 & KRT18
Clonality: Monoclonal
Clone: Clone K8.8 DC10
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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