Anti-ESR2 Mouse Monoclonal Antibody (CF660R) [clone: ESR2/686]

Supplier: Biotium

BNC610686-100 BNC610686-500

75926-308EA 325.12 CAD

75926-308 75926-310

Anti-ESR2 Mouse Monoclonal Antibody (CF660R) [clone: ESR2/686]

Antibodies

Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®660R is a far-red fluorescent dye (Ex/Em 663/682 nm) with superior brightness and unrivaled photostability among spectrally similar dyes.

Type: Primary
Antigen: ESR2
Clonality: Monoclonal
Clone: Clone ESR2/686
Conjugation: CF660R
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Human

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