Anti-VWF Mouse Monoclonal Antibody (Biotin) [clone: 3E2D10 VWF635]

Supplier: Biotium

BNCB0646-100 BNCB0646-500

75979-588EA 325.12 CAD

75979-588 75979-590

Anti-VWF Mouse Monoclonal Antibody (Biotin) [clone: 3E2D10 VWF635]

Antibodies

von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Type: Primary
Antigen: VWF
Clonality: Monoclonal
Clone: Clone 3E2D10 VWF635
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human

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