Anti-CD14 Mouse Monoclonal Antibody (CF488A) [clone: LPSR/553]

Supplier: Biotium

BNC880553-100 BNC880553-500

75887-334EA 325.12 CAD

75887-334 75887-336

Anti-CD14 Mouse Monoclonal Antibody (CF488A) [clone: LPSR/553]

Antibodies

This antibody recognizes a protein of 55 kDa, identified as CD14 (also known lipopolysaccharide receptor). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: CD14
Clonality: Monoclonal
Clone: Clone LPSR/553
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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