Anti-KRT14 Mouse Monoclonal Antibody (CF594) [clone: LL002]

Supplier: Biotium

BNC940499-100 BNC940499-500

75916-292EA 325.12 CAD

75916-292 75919-120

Anti-KRT14 Mouse Monoclonal Antibody (CF594) [clone: LL002]

Antibodies

Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: KRT14
Clonality: Monoclonal
Clone: Clone LL002
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG3
Reactivity: Human, Mouse, Rat

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