Anti-KRT14 Mouse Monoclonal Antibody (CF647) [clone: LL002]

Supplier: Biotium

BNC470499-100 BNC470499-500

75919-126EA 325.12 CAD

75919-126 75919-128

Anti-KRT14 Mouse Monoclonal Antibody (CF647) [clone: LL002]

Antibodies

Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: KRT14
Clonality: Monoclonal
Clone: Clone LL002
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG3
Reactivity: Human, Mouse, Rat

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