Anti-TOP1MT Mouse Monoclonal Antibody (CF594) [clone: TOP1MT/488]

Supplier: Biotium

BNC940488-100 BNC940488-500
75977-360EA 325.12 CAD
75977-360 75977-362
Anti-TOP1MT Mouse Monoclonal Antibody (CF594) [clone: TOP1MT/488]
Antibodies
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium orMore Product Information
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