Anti-TOP1MT Mouse Monoclonal Antibody (CF647) [clone: TOP1MT/488]

Supplier: Biotium

BNC470488-100 BNC470488-500
75977-368EA 325.12 CAD
75977-368 75977-370
Anti-TOP1MT Mouse Monoclonal Antibody (CF647) [clone: TOP1MT/488]
Antibodies
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium orMore Product Information
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SPECIFICATIONS

Antigen symbol TOP1MT
Environmentally Preferable
Antigen name Topoisomerase I MT
Antibody type Primary
Clonality Monoclonal
Conjugation CF® 647
Clone TOP1MT/488
Reactivity Human
Host Mouse
Gene ID Unigene ID: 528574
Isotype IgG2b kappa
ImmunoChemistry Yes
ImmunoFluorescence Yes
Concentration 0.1 mg/mL
Storage buffer PBS/0.1% BSA/0.05% azide

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