Anti-ODC1 Mouse Monoclonal Antibody (CF488A) [clone: ODC1/487]

Supplier: Biotium

BNC880487-500 BNC880487-100

75966-762EA 900.17 CAD

75966-762 75968-784

Anti-ODC1 Mouse Monoclonal Antibody (CF488A) [clone: ODC1/487]

Antibodies

This antibody recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: ODC1
Clonality: Monoclonal
Clone: Clone ODC1/487
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human, Rat

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