Anti-CD8A Mouse Monoclonal Antibody (Biotin) [clone: C8/468]

Supplier: Biotium

BNCB0468-100 BNCB0468-500
75907-918EA 325.12 CAD
75907-918 75907-920
Anti-CD8A Mouse Monoclonal Antibody (Biotin) [clone: C8/468]
Antibodies
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 α/β) or as a homodimer (CD8 α/α). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas areMore Product Information
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