Anti-CD44 Mouse Monoclonal Antibody (CF647) [clone: 156-3C11]

Supplier: Biotium

BNC470460-100 BNC470460-500

75911-168EA 325.12 CAD

75911-168 75911-170

Anti-CD44 Mouse Monoclonal Antibody (CF647) [clone: 156-3C11]

Antibodies

This antibody recognizes a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. This MAb selectively interferes with lymphocyte binding to lymph node, mucosal and synovial endothelium. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: CD44
Clonality: Monoclonal
Clone: Clone 156-3C11
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Baboon, Green monkey, Human

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