Anti-ERBB2 Mouse Monoclonal Antibody (CF405S) [clone: HRB2/451]

Supplier: Biotium

BNC040451-100 BNC040451-500

75952-720EA 325.12 CAD

75952-720 75952-722

Anti-ERBB2 Mouse Monoclonal Antibody (CF405S) [clone: HRB2/451]

Antibodies

This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: ERBB2
Clonality: Monoclonal
Clone: Clone HRB2/451
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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