Anti-EGFR Mouse Monoclonal Antibody (CF488A) [clone: GFR450]

Supplier: Biotium

BNC880450-100 BNC880450-500

75924-596EA 325.12 CAD

75924-596 75924-598

Anti-EGFR Mouse Monoclonal Antibody (CF488A) [clone: GFR450]

Antibodies

This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: EGFR
Clonality: Monoclonal
Clone: Clone GFR450
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human

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