Anti-EGFR Mouse Monoclonal Antibody (CF405S) [clone: GFR450]

Supplier: Biotium

BNC040450-100 BNC040450-500

75924-592EA 325.12 CAD

75924-592 75924-594

Anti-EGFR Mouse Monoclonal Antibody (CF405S) [clone: GFR450]

Antibodies

This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: EGFR
Clonality: Monoclonal
Clone: Clone GFR450
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human

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