Anti-CD47 Mouse Monoclonal Antibody [clone: B6H12.2]

Supplier: Biotium

BNUB0437-100 BNUB0437-500

75913-704EA 380.65 CAD

75913-704 75913-706

Anti-CD47 Mouse Monoclonal Antibody [clone: B6H12.2]

Antibodies

This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Type: Primary
Antigen: CD47
Clonality: Monoclonal
Clone: Clone B6H12.2
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human, Mouse

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