Anti-PODXL Mouse Monoclonal Antibody (CF405S) [clone: 3D3]

Supplier: Biotium

BNC040427-100 BNC040427-500

75971-340EA 325.12 CAD

75971-340 75971-342

Anti-PODXL Mouse Monoclonal Antibody (CF405S) [clone: 3D3]

Antibodies

Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: PODXL
Clonality: Monoclonal
Clone: Clone 3D3
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Rabbit, Rat

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