Anti-IL2RA Mouse Monoclonal Antibody (CF405S) [clone: IL2RA/423]

Supplier: Biotium

BNC040423-100 BNC040423-500
75891-210EA 325.12 CAD
75891-210 75891-212
Anti-IL2RA Mouse Monoclonal Antibody (CF405S) [clone: IL2RA/423]
Antibodies
This antibody recognizes a protein of 55 kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1 adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb This antibody recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: IL2RA
Clonality: Monoclonal
Clone: Clone IL2RA/423
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human
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