Anti-NEFH Mouse Monoclonal Antibody [clone: NF421]

Supplier: Biotium

BNUB0421-100 BNUB0421-500

75965-578EA 380.65 CAD

75965-578 75965-580

Anti-NEFH Mouse Monoclonal Antibody [clone: NF421]

Antibodies

This MAb reacts with a 200 kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Type: Primary
Antigen: NEFH
Clonality: Monoclonal
Clone: Clone NF421
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Chicken, Human, Mouse, Pig, Rat

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