Anti-CHGA Mouse Monoclonal Antibody (CF594) [clone: CHGA/413]

Supplier: Biotium

BNC940413-100 BNC940413-500

75909-794EA 325.12 CAD

75909-794 75909-796

Anti-CHGA Mouse Monoclonal Antibody (CF594) [clone: CHGA/413]

Antibodies

Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: CHGA
Clonality: Monoclonal
Clone: Clone CHGA/413
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Human

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