Anti-CHGA Mouse Monoclonal Antibody (CF568) [clone: CHGA/413]

Supplier: Biotium

BNC680413-100 BNC680413-500

75909-790EA 325.12 CAD

75909-790 75909-792

Anti-CHGA Mouse Monoclonal Antibody (CF568) [clone: CHGA/413]

Antibodies

Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Type: Primary
Antigen: CHGA
Clonality: Monoclonal
Clone: Clone CHGA/413
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Human

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