Anti-BCL10 Mouse Monoclonal Antibody (CF594) [clone: BL10/411]

Supplier: Biotium

BNC940411-100 BNC940411-500

75884-514EA 325.12 CAD

75884-514 75884-516

Anti-BCL10 Mouse Monoclonal Antibody (CF594) [clone: BL10/411]

Antibodies

BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFkB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: BCL10
Clonality: Monoclonal
Clone: Clone BL10/411
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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