Anti-TIMP3 Rabbit Polyclonal Antibody (CF647) [clone: Rabbit PAb]

Supplier: Biotium

BNC470408-100 BNC470408-500

75980-898EA 325.12 CAD

75980-898 75980-900

Anti-TIMP3 Rabbit Polyclonal Antibody (CF647) [clone: Rabbit PAb]

Antibodies

TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: TIMP3
Clonality: Polyclonal
Clone: Clone Rabbit PAb
Conjugation: CF647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Cow, Dog, Horse, Human, Mouse, Rat

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