Anti-TIMP3 Rabbit Polyclonal Antibody (CF647) [clone: Rabbit PAb]

Supplier: Biotium

BNC470408-100 BNC470408-500
75980-898EA 325.12 CAD
75980-898 75980-900
Anti-TIMP3 Rabbit Polyclonal Antibody (CF647) [clone: Rabbit PAb]
Antibodies
TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellularMore Product Information
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