Anti-CD28 Mouse Monoclonal Antibody (CF488A) [clone: CB28]

Supplier: Biotium

BNC880384-100 BNC880384-500

75891-838EA 325.12 CAD

75891-838 75891-840

Anti-CD28 Mouse Monoclonal Antibody (CF488A) [clone: CB28]

Antibodies

This antibody recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: CD28
Clonality: Monoclonal
Clone: Clone CB28
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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